SAN2016 Blog

Evaluating the Course of an Alzheimer’s Disease Model in the Rat Brain with High Frequency Ultrasound

By Georgios Karagiannis

Acoustic microscopy is a novel non-invasive and relatively safe method of imaging internal organs and structures. The presented work involved the application of acoustic microscopy in an attempt to reveal composite topographic changes in the brain due to Alzheimer’s disease. The experiment included mice injected with streptozotocin and successfully identified the hippocampal alterations. Time-frequency signal processing of the resulting images of the acoustic microscope was proposed for future work. 

Fluoxetine is an effective treatment to reduce respiratory distress in Necdin deficient mice

By Valery Matarazzo

The speaker initiated his presentation with the well-known antidepressant Prozac® and its side effects on babies. The aim of the research was to detect the gene that was absent due to Prozac® consumption during pregnancy on mice and try to cure the symptoms of sleep apnea by gene therapy. The speaker remarked that even though the gene therapy was successful, the effects didn’t last to adulthood.

The interesting discussion circled around other possible therapies such as serotonin and oxytocin. 

Experimental model of brain oedema in rats

By Jaroslav Pokorny

The speaker presented his experimental research on the pathophysiology of brain cell oedema on rats. The research team created a model of brain cells during an oedema by water intoxication. The model was successfully validated by CT scans and MRI of hyper hydrated rats. The model can be used in future research on protecting the neurons and the cellular membrane in general.

Following the presentation took place a fruitful discussion on the possibilities of application to humans and ways to improve and even expand the model. 

Neurofeedback state of play: a nascent field

By John Gruzelier

The invited speaker surprised the audience by changing the presentation to a review of the history of Society of Applied Neuroscience. The main focus was neurofeedback and its path to the current state of the art. Excited the audience, paid careful attention to the timeline that lead it to attend the conference. He provided an extensive review of the learning curve of neurofeedback and presented milestone researches that brought NF to this point. Additionally, to the timeline review, the speaker presented the theoretical assumptions underlying neurofeedback.

Sleep, memory, attention and Neurofeedback

Prof Ioannides initiates the talk with cues from his keynote mentioning the parallel of Neurofeedback application to the intuitiveness of mother’s activities to the child. The focus in this approach is the individuality of NF interventions. While average networks are similar there are personal variations which are heavily accented in disease contexts. After that, some interesting philosophical overtures are discussed about variations in neuronal activity, the self and the Heracletan approach of dynamics and change.

Neuroscience and Music

Dr. Evangelos Paraskevopoulos was the last presenter of the session on neurosciences and music. He focused on statistical learning and presented a functional connectivity analysis identifying the significant contribution of musical training in the reorganization of the cortical networks subserving statistical learning. The results initiated a discussion for the role of Inferior Frontal Gyrus in statistical learning as well as the timing of processing of statistically learned tones from the auditory cortex.

Coffee & cozy style invited talk

The participants of the conference were strongly surprised by this cozy style installation introduced by Eleni Fotiadou. Fotiadou is a Greek, London based audiovisual artist with various participations and solo exhibitions. Her artwork has been presented in public spaces including the European Parliament. Neuroaisthetics has been a strong driving force on her work and especially in the interesting installation she presented in this part of the conference.

The Quadrato Motor Training model: implications to the treatment of Alzheimer and Parkinson’s disease

Dr. Tal Dotan Ben-Soussan presents interesting results about physiological and structural changes in PD and Alzheimer’s disease and the mechanisms that these are brought about in these diseases. The overall aim is to have a healthy aging population away from age prevalent diseases like Alzheimer’s and PD.

Personalized Game Suite: A unified platform to sustain and improve the Quality of Life of Parkinson’s Disease patients

Sofia B. Dias kicks of the session with the description of a personalized game suite for improving the quality of life for PD patients. The talk introduces the role of games in healthcare interventions and describes the gap that exists for app/games in manageable chronic diseases like PD. It then moves to describe specific gamification design issues and tie them with the needs for intelligent early detection and intervention in PD. The gaming suite described includes a host of games including exergames, dietary games and other goal oriented activities.

Neuroscience and Music

Dr Clément François, presented a very interesting study performed in adults and children, which shows that the music practice and training, enhance the sensitivity to statistical regularities in speech at behavioral and neural levels.

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