The Quadrato Motor Training model: implications to the treatment of Alzheimer and Parkinson’s disease

Sunday, October 9, 2016 - 12:15
Blog post content: 

Dr. Tal Dotan Ben-Soussan presents interesting results about physiological and structural changes in PD and Alzheimer’s disease and the mechanisms that these are brought about in these diseases. The overall aim is to have a healthy aging population away from age prevalent diseases like Alzheimer’s and PD.

The role of NGF and proNGF is discussed in these diseases and the rationale for them as markers for assessing the efficacy of the quadratomotor training. Moving on to phenotypic expressions like creativity it is related to both NGF and proNGF a negative correlation between creativity and proNGF is revealed.

Moving to BDNF and proBDNF results which are also markers for healthy brain function whereas in Alzheimer’s proBDNF is reduced. Effects like increase after physical exercise regimes is also discussed.

Quadratto motor training, then, is detailed with focus on the alpha rhythm changes after QMT. Moving to functional connectivity expression in Alzheimer’s and PD deviations from the healthy baseline is explored and its role as a training marker is explored.

After this rigorous introduction an equally rigorous description of the methodology of the study is followed.  Results demonstrate that QMT induces a functional connectivity enhancement from right occipital to right parietal and temporal rsEEG source activity. Interestingly enough QMT has the same effect in healthy subjects.

The novelty of the study is explored and, concluding, the positive effects of QMT are summarized. These results demonstrate QMT as a valid intervention against neurodegenerative diseases.

The presentation ended with a novel activity exercise for demonstrating the effects of it on the physical emotional and cognitive state.